“Good” cholesterol helps prevent breakaway BLOOD CLOTS.

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December 2007


“Good” cholesterol helps prevent breakaway BLOOD CLOTS. Having a high level of high-density lipoprotein (HDL, or “good”) cholesterol appears to help prevent a second occurrence of venous thromboembolism. That’s when a piece of a blood clot that develops in a deep leg vein breaks off and is swept into the bloodstream; it may lodge in an artery in a lung, creating a life-threatening situation. A research team tracked a total of 772 men and women for an average of 4 years after their first experience with venous thromboembolism. Compared with those who had no repeat episodes during the follow-up period, the 100 individuals who suffered another thromboembolism had significantly lower levels of apolipoprotein AI—the major protein in HDL cholesterol. In addition, the repeat-episode group had markedly lower levels of HDL cholesterol. Further research may show that raising HDL levels through lifestyle changes or medication could reduce the risk of recurring venous thromboembolism.

Circulation, a journal of the American Heart Association

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December 2007